| Number of compounds |
1,120 |
| Plate Numbers |
1568-1571 (4 Plates) |
| Concentration Information |
2 mg/ml in DMSO |
| Plate Format |
384-well Plate
Plates 1568-1570:
Columns 1-2 and 23-24 (empty)
 Click plate image to enlarge
Plate 1571:
Partial plate, see details below
 Click plate image to enlarge
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The Prestwick library was purchased by the New England Regional Center of Excellence in Biodefense and Emerging Infectious Diseases (NERCE/BEID) in February 2006. This library contains 1120 off-patent compounds that have been selected for structural diversity, collective coverage of multiple therapeutic areas, and known safety and bioavailability in humans. Over 85% of the Prestwick compounds are marketed drugs.
Investigators wishing to screen the maximum number of FDA-approved drugs can achieve approximately 46% coverage (561 compounds) of the FDA set by screening both NINDS and Prestwick. Including the ICCB Biomol Known Bioactives will increase coverage to ~47% of the FDA set, as there is some redundancy among these three libraries.
Many of the compounds in the Prestwick library can be obtained from Sigma-Aldrich, but they can also be ordered directly from Prestwick:
Prestwick Chemical, Inc.
Mona DePoitiers Rudnicki
1825 K Street NW Suite 1475
Washington, DC 20006
Click here to view a complete list of the compounds in this collection
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