ICBG Fungal Extracts 1


Number of extracts

851

Plate Numbers

1453-1455 (3 Plates)

Concentration Information

Dried extracts resuspended at ~15 mg/ml in DMSO

Plate Format

384-well plate

Plates 1453-1454:
Column 23-24 (empty)

Click plate image to enlarge

Plate 1455:
Column 11-24 [A-I] (empty)
Column 10-24 [J] (empty)
Column 9-24 [K-P] (empty)

Click plate image to enlarge

These compounds were received over a period of time in 2004, therefore plate 1453 was plated in late August 2004, and plates 1454 and 1455 were plated in November 2004. Production of this fungal extract library was funded by an International Cooperative Biodiversity Groups (ICBG) grant from the NIH to Dr. Jon Clardy. The library contains partially purified extracts from endophytic fungi (fungi that live in higher plants) that grow in Costa Rica. Crude extracts from the fungi were obtained and further fractionated to eliminate nuisance compounds, especially those of high molecular weight or high polarity.

Screening positives that have been confirmed by follow-up experiments on cherry picked samples can be further fractionated via a collaboration with the lab of Dr. Jon Clardy (Harvard Medical School). Please contact Caroline Shamu (caroline_shamu@hms.harvard.edu) to arrange for purification of "hit" compounds from extract samples.